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Heritage and Apotex to pay $49.1M in price-fixing settlement

Generic drug manufacturers Heritage Pharmaceuticals and Apotex have agreed to pay $49.1 million to settle allegations from nearly all US states that the companies inflated and manipulated drug prices...

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Maven Clinic cuts 10% of workforce weeks after raising $125M

Maven Clinic laid off 60 people on Monday, Endpoints News has learned. The layoffs at the unicorn health tech startup represented about 10% of its workforce and happened across the organization,...

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BMS, J&J and AstraZeneca plea with appeals court to overturn drug price...

A panel of three judges on the US Court of Appeals for the Third Circuit didn't offer too many hints at which side it would take as it heard oral arguments on Wednesday from a ...

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How RFK Jr. might influence the FDA; Pharma's Q3 highlights; AbbVie's latest...

Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...

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CinRx touts positive data from two obesity drug candidates

CinFina Pharma, a subsidiary of the hub-and-spoke biotech CinRx, shared early-stage data for two of its Janssen-licensed obesity candidates at this year’s ObesityWeek. CIN-110, a PYY analog, and...

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Novo adds to Wegovy’s cardio strength with hospital admissions analysis

SAN ANTONIO — Novo Nordisk’s wildly popular anti-obesity drug Wegovy helped heart disease patients end up in the hospital less often and stay there for shorter durations than those on placebo,...

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Viking oral weight loss drug shows promising Phase 1 data

SAN ANTONIO — Viking Therapeutics' highly anticipated readout of its oral anti-obesity pill showed a placebo-adjusted weight loss of 6.8% after four weeks, sticking the biotech near the front of a...

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European Commission marks Dec. 6 for Novo-Catalent deal decision

The European Commission has set Dec. 6 as its deadline to decide if Novo Holdings’ multi-billion-dollar acquisition of Catalent passes its antitrust review, according to a notification on its website. ...

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MASH drug developers chart path forward as more patients use GLP-1s

For years, drug developers working to treat an advanced form of fatty liver disease known as MASH were chasing wide-open terrain. There were no products on the market, millions of potential patients...

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'We play to win': AstraZeneca details first results for oral GLP-1 and...

SAN ANTONIO — Well behind Novo Nordisk and Eli Lilly in the obesity race, AstraZeneca came to this year's ObesityWeek with three assets in hand as it hopes to "move beyond short-term weight loss" and ...

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Novo, Ascendis to work on monthly GLP-1; KalVista makes a royalty deal

Plus, news about Disc Medicine, OSE Immunotherapeutics, CrossBridge Bio, Lomond Therapeutics, Relief Therapeutics and Renexxion: Novo Nordisk, Ascendis Pharma ink deal: The Danish drugmaker will pay up...

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BioNTech says VEGF bispecific’s PD-L1 target, combo plans will be its edge

BioNTech said that its VEGF bispecific sets it apart from competitors because of its mechanism and how it plans to investigate the asset in combination with other modalities. During the German...

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FDA expands faster drug review pilot from supplemental to full applications

The FDA on Dec. 2 will open up an expedited review pilot program that's meant to speed therapies that substantially improve upon what's currently available for serious conditions to full marketing...

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BioNTech eases 2024 revenue outlook despite hefty Covid vaccine third-quarter...

Despite strong third-quarter revenues, BioNTech has softened its 2024 sales guidance in light of changes to Covid-19 vaccine uptake, pricing and seasonal variations. The company’s €1.2 billion ($1.3...

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Rare disease biopharma companies weigh in on FDA's new innovation hub

AstraZeneca's Alexion, BridgeBio, BioMarin, Ultragenyx and others, including Sen. Bob Casey (D-PA), recently weighed in on the details of a new cross-cutting FDA collaboration hub focused on rare...

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The election is Tuesday. What’s at stake for the pharma industry?

The biopharma industry has been a bipartisan political target in recent years. But in the 2024 presidential election, details are scarce around key issues that could impact drugmakers. Drug pricing has...

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FDA cites Mark Cuban's drug compounding center in Dallas with sterility,...

The FDA is raising sterility and other quality concerns with Mark Cuban's Cost Plus Drugs compounding facility in Dallas, following a nine-day inspection of the site in August and September. A

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