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Gilead buys experimental HIV vaccines from a small Barcelona biotech

Long known for its HIV drugs, Gilead is further delving into the field by acquiring investigational vaccines for the stubborn virus from a little-known biotech in Spain. Gilead is paying an undisclosed...

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Replimune aims to raise $125M; Otsuka makes another deal with Ionis

Plus, news about Kanglin Biotechnology, Seelos, Orbus and Sonata: Replimune’s $125M offering: The biotech announced the offering four days after it submitted an FDA application for RP1 ...

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Biohaven's myostatin inhibitor misses primary endpoint in spinal muscular...

Biohaven’s stock fell in premarket trading on Monday after it announced a Phase 3 trial failure of its myostatin inhibitor in spinal muscular atrophy and obesity. The RESILIENT study did not ...

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Cassava shares plunge as controversial Alzheimer’s drug fails Phase 3 trial

Is this the end for Cassava Sciences? After a problematic development path riddled with allegations of misleading investors, the biotech’s Alzheimer’s drug flopped on all endpoints in a Phase 3 study....

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#ASH24: Incyte touts Monjuvi data from Phase 3 follicular lymphoma trial as...

Incyte’s monoclonal antibody Monjuvi reduced certain follicular lymphoma patients’ risk of progression, relapse or death by 57% compared to placebo, the company announced Monday. The Phase 3 data,...

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Merck halts Phase 3 trial with PAH drug Winrevair following positive interim...

Merck is stopping a Phase 3 trial of its pulmonary arterial hypertension treatment Winrevair almost a year early following positive interim data, the company announced Monday. The trial, which was...

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Minnesota 340B revenue driven by hospitals and high-priced drugs, first state...

As the federal drug discount program known as 340B has seen rapid growth in recent years, Minnesota's Department of Health is looking to shine a light on where that growth is occurring. The first year ...

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Trump team asked Covid vaccine leader about heading NIH

The transition team for President-elect Donald Trump was still searching for its next National Institutes of Health director as recently as last week, multiple sources told Endpoints News, potentially...

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Bristol Myers reveals more job cuts in New Jersey

Bristol Myers Squibb's cost-cutting initiative will lead to additional layoffs in Lawrenceville, NJ, the company revealed this month in a state WARN notice. A total of 197 cuts, some of which ...

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How did Trump’s FDA pick land? Biotech stocks are up, and executives are...

Now that President-elect Donald Trump has made his choice for FDA commissioner, reactions and analysis are pouring in from biopharma executives and former staffers who know the agency’s inner workings....

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Alector says Alzheimer's program targeting microglia fails Phase 2, stock dives

Alector reported a Phase 2 failure for an AbbVie-partnered Alzheimer’s program Monday afternoon and said it will need to lay off staff. Researchers were examining whether the drug, known as AL002,...

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Why Morgan Health is backing autism care provider Cortica

JP Morgan’s Morgan Health is rounding out its first three years of investing with its seventh investment. The health venture, which the bank launched to get a handle on healthcare costs for ...

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Cradle Bio raises $73M Series B for protein-making AI software

European startup Cradle Bio raised a $73 million Series B round, fueling its plans to sell its AI-based protein-making software to more drugmakers. Cradle was founded in December 2021 by a team ...

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Roche’s TIGIT drug misses overall survival endpoint in Phase 3 lung cancer trial

Roche’s TIGIT drug has failed to clear the final hurdle in a late-stage cancer trial in what’s proving to be a mostly disappointing year for a drug class that was once seen as the next ...

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Roche buys out CAR-T partner Poseida for $1B upfront

Roche is acquiring its cell therapy and genomic medicines partner Poseida Therapeutics, the companies said Tuesday morning. The Basel-based pharma giant will pay $9 per share in upfront cash, giving...

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Updated: Amgen obesity shot shows 20% weight loss, but dosing questions hang...

Amgen said its experimental weight loss drug MariTide helped obese patients lose 20% of their weight after a year of treatment with the shot. And while it was touted as a win, the data immediately ...

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Aviceda aims to raise $200M; Nerviano gets back rights to PARP1 inhibitor

Plus, news about Maat Pharma, Secretome Therapeutics, 35Pharma, Medigene and Doron Therapeutics: Aviceda Therapeutics’ $200M financing: The Boston-area biotech is looking to raise a $200 million equity...

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Agilent reveals plans to remodel operations as annual revenue dips

CDMO and laboratory product developer Agilent Technologies has unveiled a reshuffle its business model, which will see the consolidation of operations and build up new business priorities. These moves...

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Soleno’s rare pediatric disease drug faces PDUFA delay by three months

Soleno Therapeutics may have to wait longer to hear from the FDA on the potential approval of its first medicine. The California biotech said Tuesday the agency extended the review period ...

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Food allergy biotech Alladapt closes after Phase 3 talks with FDA

Alladapt Immunotherapeutics, a well-financed biotech working in the food allergy field, shut down following talks with the FDA, according to a source familiar with the company. After claiming success...

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